8/5/2023 0 Comments In motion fitness inc logo![]() ![]() The products showed robust efficacy in animal studies. The lead products are StemGel for osteoarthritis and TenGel for tendon injury. WNT Scientific LLC USA Private Wnt Scientific is a preclinical stage company developing the therapeutics for joint diseases. The cmpany's pipeline includes: Neurofibromatosis Type 2 Cerebral Cavernous Malformation GM2 Gangliosidosis Solid Tumors Dilated Cardiomyopathy Clostridium difficile Colitis Neuroinflammation Batten Disease Charcot-Marie-Tooth Disease Pulmonary Arterial Hypertension Senescence Vascular Disease Oncology Gaucher Disease. Recursion USA Listed We are Reengineering drug discovery by taking a target-agnostic approach that combines automation, machine learning and the world’s largest biological image dataset with a highly cross-functional team to discover transformative new treatments. Addex's allosteric modulator drug discovery platform targets receptors and other proteins that are recognized as essential for therapeutic intervention. Allosteric modulators offer several potential advantages over conventional non-allosteric molecules and may offer an improved therapeutic approach to conventional "orthosteric" small molecule or biological drugs. Seed funding and additional corporate funding has been provided by the peer-reviewed biotech support program of the Alzheimer's Drug Development Foundation (ADDF).Īddex Therapeutics Switzerland Listed Addex Therapeutics is a clinical-stage pharmaceutical company focused on the development and commercialization of an emerging class of novel orally available small molecule drugs known as allosteric modulators for neurological disorders. He serves as Chairman of the Board of PTX and as a consultant. Longo, MD, PhD during his tenure at UNC - Chapel Hill. This virtual model is recognized as an effective way of minimizing overhead costs while efficiently achieving drug development milestones. ![]() ![]() PTX is operated as a virtual biotech company in Menlo Park, CA executing drug development through contracted work. PharmatrophiX USA Private PharmatrophiX (PTX) is a privately held biopharmaceutical company focused on the development of disease-modifying small molecule drugs targeting mechanisms underlying neurodegenerative and other disorders. Lmito focuses on modulating cell metabolism to develop new immunotherapeutic compounds in immunology, neuro-immunology, and immuno-oncology. South Korea Private Lmito Therapeutics was founded with the purpose of discovering the first curative therapy for mitochondrial disorders using disease-modifying treatment that extended beyond symptom alleviation. As the first compounds that directly improve mitochondrial dynamism, approval of mitofusin activators opens the door to a new and fundamentally different therapeutic approcach to ND. MiM’s compounds bind to MFNs, altering their conformation to enhance activity, and thereby mitochondrial fitness. Similar neuronal mitochondrial phenotypes are observed in CMT1, ALS, HD, frontotemporal dementia, and CIPN. With no disease-altering therapy, most CMT2A affected children are permanently non-ambulatory by age 20. Loss of MFN2 function suppresses mitochondrial fusion and trafficking. Our first indication is Charcot-Marie-Tooth disease (CMT)2A, caused by mutations of our drugs’ target, mitofusin (MFN)2. that will clinically advance and commercialize first-in-class mitofusin activators which improve mitochondrial function by correcting mitochondrial dys-dynamism in genetic, traumatic, and iatrogenic neurodegenerative diseases (ND). Mitochondria in Motion, (MiM) is a biotech Co. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |